Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Tufts University

US Patent

LigandBDBM112784(US8628961, PIT-1)Copy SMILESCopy InChI

Affinity DataIC50:  3.10E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

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In DepthDetails US Patent
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TargetCytohesin-3(Homo sapiens (Human))
Tufts University

US Patent

LigandBDBM112784(US8628961, PIT-1)Copy SMILESCopy InChI

Affinity DataIC50:  4.03E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

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In DepthDetails US Patent
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Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Tufts University

US Patent

LigandBDBM112784(US8628961, PIT-1)Copy SMILESCopy InChI

Affinity DataIC50:  6.67E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI