Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50112575(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50112575(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI