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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50400179
(2,3‐dihydroxy‐6‐(phenylsulfanyl)...)
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Affinity Data
Ki: 53nM
Assay Description:
Binding affinity to Mcl-1 after 30 mins by florescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50400179
(2,3‐dihydroxy‐6‐(phenylsulfanyl)...)
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Copy InChI
Affinity Data
Ki: 71nM
Assay Description:
Binding affinity to Bcl-2 after 30 mins by florescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Induced myeloid leukemia cell differentiation protein Mcl-1 [172-327]
(Homo sapiens (Human))
Dalian University Of Technology
Ligand
BDBM50400179
(2,3‐dihydroxy‐6‐(phenylsulfanyl)...)
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Copy InChI
Affinity Data
Kd: 1.47E+3nM
pH: 8.0 T: 2°C
Assay Description:
ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI