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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Aromatase
(Homo sapiens (Human))
Universidade De Coimbra
Curated by
ChEMBL
Ligand
BDBM50254017
(6-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)benzo[...)
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Affinity Data
Ki: 1.90nM
Assay Description:
Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPH
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Aromatase
(Homo sapiens (Human))
Universidade De Coimbra
Curated by
ChEMBL
Ligand
BDBM50254017
(6-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)benzo[...)
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Copy InChI
Affinity Data
IC50: 5.30nM
Assay Description:
Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPH
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein disulfide-isomerase
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM50254017
(6-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)benzo[...)
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Copy InChI
Affinity Data
IC50: 670nM
Assay Description:
Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI