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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataKi:  1.89E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine substrate by flurometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine substrate by flurometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50:  2.15E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed