Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAlpha-synuclein(Homo sapiens (Human))
Proteotech

US Patent

LigandBDBM170550(US9085549, 54)Copy SMILESCopy InChI

Affinity DataKi:  1.64E+3nMpH: 7.4Assay Description:The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Proteotech

US Patent

LigandBDBM170550(US9085549, 54)Copy SMILESCopy InChI

Affinity DataIC50:  7.34E+3nMAssay Description:The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI