Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  42nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed