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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
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Affinity Data
Ki: 0.0610nM
Assay Description:
The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0610nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0610nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.340nM
Assay Description:
Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain membrane by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.340nM
Assay Description:
Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.340nM
Assay Description:
In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
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Affinity Data
Ki: 0.410nM
Assay Description:
Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
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Affinity Data
Ki: 0.410nM
Assay Description:
Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain membrane by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.410nM
Assay Description:
In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.480nM
Assay Description:
Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.480nM
Assay Description:
In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin II
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0790nM
Assay Description:
The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0790nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0790nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.0750nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Alkermes Pharma Ireland
US Patent
Ligand
BDBM50249017
(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.0750nM
Assay Description:
The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI