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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
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Affinity Data
Ki: 4.90nM
Assay Description:
Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.40nM
Assay Description:
Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50002078
(CHEMBL611396)
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Copy InChI
Affinity Data
Ki: 6.5nM
Assay Description:
Binding affinity against Opioid receptor delta 1 from rat brain membranes using [3H]DADLE
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 89nM
Assay Description:
Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
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Affinity Data
Ki: 175nM
Assay Description:
Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 220nM
Assay Description:
Compound was tested for antagonist activity against Opioid receptor delta 1 on mouse vas deferens (MVD) smooth muscle preparation using DPDPE as anta...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Medicine & Dentistry Of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)
Curated by
ChEMBL
Ligand
BDBM50002078
(CHEMBL611396)
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Affinity Data
Ki: 234nM
Assay Description:
Binding affinity against Opioid receptor mu 1 from rat brain membranes using [3H]DAMGO
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50002078
(CHEMBL611396)
Copy SMILES
Copy InChI
Affinity Data
Ki: 234nM
Assay Description:
Binding affinity against Opioid receptor kappa 1 from guinea pig brain membranes using [3H]U-69593
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Medicine & Dentistry Of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 235nM
Assay Description:
Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 236nM
Assay Description:
Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50065856
(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Partial agonist activity expressed as inhibition of contraction of mouse vas deferens (MVD) smooth muscle at 1 uM conc.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI