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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human))
Gedeon Richter
Curated by
ChEMBL
Ligand
BDBM50134649
((6-Hydroxy-1H-indol-2-yl)-(4-phenethyl-piperidin-1...)
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Affinity Data
IC50: 24nM
Assay Description:
Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Gedeon Richter
Curated by
ChEMBL
Ligand
BDBM50134649
((6-Hydroxy-1H-indol-2-yl)-(4-phenethyl-piperidin-1...)
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Affinity Data
IC50: 359nM
Assay Description:
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Gedeon Richter
Curated by
ChEMBL
Ligand
BDBM50134649
((6-Hydroxy-1H-indol-2-yl)-(4-phenethyl-piperidin-1...)
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Copy InChI
Affinity Data
IC50: 875nM
Assay Description:
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI