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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Universit£
Curated by
ChEMBL
Ligand
BDBM50001107
(2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...)
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Affinity Data
Ki: 0.0900nM
Assay Description:
Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 in guinea pig brain homogenates
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Universit£
Curated by
ChEMBL
Ligand
BDBM50001107
(2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...)
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Copy InChI
Affinity Data
Ki: 0.0900nM
Assay Description:
Receptor binding affinity towards opioid receptor kappa
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(GUINEA PIG)
Zambeletti Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50001107
(2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...)
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Affinity Data
Ki: 0.490nM
Assay Description:
Receptor binding affinity towards opioid receptor mu
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
Zambeletti Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50001107
(2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...)
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Affinity Data
Ki: 7.10nM
Assay Description:
Receptor binding affinity towards opioid receptor delta
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Glaxo Group Research
Curated by
ChEMBL
Ligand
BDBM50001107
(2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...)
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Affinity Data
IC50: 0.110nM
Assay Description:
In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI