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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM49247
((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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Article
PubMed
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Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49247
((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)
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Affinity Data
IC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
GoogleScholar
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PCBioAssay
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Target
Nuclear hormone receptor family member daf-12
(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49247
((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)
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Affinity Data
IC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
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In Depth
Details
PCBioAssay
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Target
Transcription factor p65
(Homo sapiens (Human))
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM49247
((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)
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Affinity Data
EC50: 1.24E+3nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI