Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50206364(CHEMBL3933129)Copy SMILESCopy InChI

Affinity DataKi:  800nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50206364(CHEMBL3933129)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI