Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataKi:  364nMAssay Description:Binding affinity to alpha 1A adrenergic receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084855(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Affinity DataIC50:  2.10nMAssay Description:In vitro affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed