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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Vu University Medical Center
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
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Affinity Data
Ki: 0.330nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Vu University Medical Center
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.330nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Vu University Medical Center
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40nM
Assay Description:
Binding affinity to 5-HT1A receptor (unknown origin) assessed as inhibition constant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Beijing Normal University
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 364nM
Assay Description:
Binding affinity to alpha 1A adrenergic receptor (unknown origin) assessed as inhibition constant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Vu University Medical Center
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.770nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Vu University Medical Center
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.770nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 EBNA cells after 2 hrs by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
University Of Groningen
Curated by
ChEMBL
Ligand
BDBM50084855
(CHEMBL423361 | Cyclohexanecarboxylic acid {2-[4-(2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
Assay Description:
In vitro affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in rat hippocampus
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI