Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL

LigandBDBM50167085(CHEMBL3799623)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL

LigandBDBM50167085(CHEMBL3799623)Copy SMILESCopy InChI

Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI