Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  252nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  255nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi: >1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed