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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
NAD-dependent protein deacetylase sirtuin-1
(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by
ChEMBL
Ligand
BDBM74978
(1,3-dihydrobenzo[e]benzimidazole-2-thione | CHEMBL...)
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Affinity Data
IC50: 9.60E+3nM
Assay Description:
Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
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Article
PubMed
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Target
NAD-dependent protein deacetylase sirtuin-2
(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by
ChEMBL
Ligand
BDBM74978
(1,3-dihydrobenzo[e]benzimidazole-2-thione | CHEMBL...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Importin subunit alpha-1
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM74978
(1,3-dihydrobenzo[e]benzimidazole-2-thione | CHEMBL...)
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Affinity Data
EC50: >5.00E+5nM
Assay Description:
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
PCBioAssay
Copy BDB DOI