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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
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Target
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human))
Ucl Business
US Patent
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
IC50: 1.74E+3nM
Assay Description:
An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...
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Target
Beta-lactamase
(Klebsiella pneumoniae)
Uit The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
IC50: >2.00E+6nM
Assay Description:
Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate addition
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Target
Beta-lactamase
(Klebsiella pneumoniae)
Uit The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
Kd: >1.00E+6nM
Assay Description:
Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...
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Target
Stromelysin-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
Kd: 9.00E+5nM
Assay Description:
Binding to stromelysin (MMP-3) in the presence of 1-Napthohydroxamate
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Target
Stromelysin-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
Kd: 1.70E+5nM
Assay Description:
Binding to stromelysin (MMP-3) in the presence of acetohydroxamic acid
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Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Peregrin
(Homo sapiens (Human))
University Of Z£Rich
Curated by
ChEMBL
Ligand
BDBM50121955
(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
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Affinity Data
Kd: >2.00E+5nM
Assay Description:
Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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Article
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3D Structure (crystal)
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