Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-2A adrenergic receptor(Homo sapiens)
University Of Barcelona

Curated by ChEMBL

LigandBDBM113058(US8633208, 1)Copy SMILESCopy InChI

Affinity DataKi:  2.24E+6nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

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In DepthDetails ArticlePubMed
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TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Rottapharm

US Patent

LigandBDBM113058(US8633208, 1)Copy SMILESCopy InChI

Affinity DataIC50:  220nMAssay Description:Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Rottapharm

US Patent

LigandBDBM113058(US8633208, 1)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI