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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Astrazeneca R&D
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
Ki: 2.45E+5nM
Assay Description:
Binding affinity towards cytochrome P450 2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
MMDB
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Article
PubMed
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Target
Methionine aminopeptidase
(Escherichia coli (strain K12))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: 472nM
Assay Description:
Inhibition of Co2+ loaded MetAP expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
MCE
KEGG
MMDB
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PDB
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Article
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PDB
3D Structure (crystal)
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Target
Reverse transcriptase/RNaseH
(Human immunodeficiency virus 1)
Università
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: 1.46E+4nM
Assay Description:
HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
MMDB
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In Depth
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Article
PubMed
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Target
Methionine aminopeptidase 2
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: 4.47E+4nM
Assay Description:
Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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ChEBI
CHEMBL
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MMDB
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Article
PubMed
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Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: 4.78E+4nM
Assay Description:
Inhibition of human MetAP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
MMDB
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PC sid
PDB
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In Depth
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Article
PubMed
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Target
Multidrug and toxin extrusion protein 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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ChEBI
CHEMBL
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MCE
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
IC50: 5.60E+5nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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ChEBI
CHEMBL
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KEGG
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Article
PubMed
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Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
EC50: >1.00E+5nM
Assay Description:
Inhibition of human methionine aminopeptidase 1 in presence of Mn2+
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
MMDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
EC50: 3.40E+3nM
Assay Description:
Inhibition of human methionine aminopeptidase 1 in presence of Co2+
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
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In Depth
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Article
PubMed
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Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human))
University Of California San Diego
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
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Affinity Data
Kd: 6.00E+4nM
Assay Description:
Binding affinity to human FKBP12 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
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MMDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50121347
(CHEMBL625 | THIABENDAZOLE)
Copy SMILES
Copy InChI
Affinity Data
EC50: >2.50E+5nM
Assay Description:
Inhibition of human methionine aminopeptidase 1 in presence of Zn2+
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI