TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma
Curated by ChEMBL
Cardiome Pharma
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma
Curated by ChEMBL
Cardiome Pharma
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma
Curated by ChEMBL
Cardiome Pharma
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma
Curated by ChEMBL
Cardiome Pharma
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma
Curated by ChEMBL
Cardiome Pharma
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of Kv2.1 channel (unknown origin) by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 2.23E+4nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair