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Found 13 Enz. Inhib. hit(s) with Target = 'DNA ligase A'
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22982(Glycosyl Ureides, 3b | ethyl 3-[(3aS,6R,6aS)-6-(be...)
Affinity DataIC50:  4.00E+3nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22982(Glycosyl Ureides, 3b | ethyl 3-[(3aS,6R,6aS)-6-(be...)
Affinity DataIC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22981(Glycosyl Ureides, 3a | ethyl 3-[(3aS,6R,6aS)-6-(be...)
Affinity DataIC50:  9.65E+3nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22981(Glycosyl Ureides, 3a | ethyl 3-[(3aS,6R,6aS)-6-(be...)
Affinity DataIC50:  9.65E+3nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22983(ethyl 3-[({3-[({1-[(3aR,6S,6aR)-6-(benzyloxy)-2,2-...)
Affinity DataIC50:  2.77E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM93107(Arylamino compound, 1)
Affinity DataIC50:  4.60E+4nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataIC50:  4.60E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataIC50:  4.60E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM50487370(CHEMBL2259939)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis LigAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase A(Mycobacterium tuberculosis)
Central Drug Research Institute

LigandPNGBDBM93108(Glycosylamine, 4)
Affinity DataIC50:  4.62E+4nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article