TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 3.85nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 5.01nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 6.09nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 6.10nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 6.49nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 6.5nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 7.25nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 7.30nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 8.28nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 13.6nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 14nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 19.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 20nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 25nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2 [E242G,S244A,Q278R,I281T,K282R,R316G,P318T,Y321CH323L](Mus musculus (Mouse))
National Institutes Of Health
National Institutes Of Health
Affinity DataIC50: 29nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 32.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 33nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 33.1nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 35nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 35nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 38nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 38nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 39nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 40nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 40nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 41nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 42nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 47nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 59nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 62nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 64.7nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 65nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 70nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 70.4nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 130nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 131nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 140nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 140nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 150nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 153nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 161nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2 [E242G,S244A,Q278R,I281T,K282R,R316G,P318T,Y321CH323L](Mus musculus (Mouse))
National Institutes Of Health
National Institutes Of Health
Affinity DataIC50: 170nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 180nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 185nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 186nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota
US Patent
Regents Of The University Of Minnesota
US Patent
Affinity DataIC50: 190nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair