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Found 152 Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4'
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330742(2-(2-Chlorophenyl)-5-[(1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataKi:  47nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330740(2-(2-chlorophenyl)-4-((4-(3-methoxyphenyl)piperazi...)
Affinity DataKi:  65nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  67nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359523(CHEMBL1927147)
Affinity DataKi:  72nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359528(CHEMBL1927149)
Affinity DataKi:  76nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330744(4-((2-chlorobenzyloxy)methyl)-2-(2-chlorophenyl)-5...)
Affinity DataKi:  82nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359525(CHEMBL1927146)
Affinity DataKi:  87nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359520(CHEMBL1927158)
Affinity DataKi:  93nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359518(CHEMBL1927156)
Affinity DataKi:  94nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330743(4-(benzyloxymethyl)-2-(2-chlorophenyl)-5-(pyrazin-...)
Affinity DataKi:  95nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359529(CHEMBL1927150)
Affinity DataKi:  101nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359534(CHEMBL1927155)
Affinity DataKi:  111nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359531(CHEMBL1927152)
Affinity DataKi:  111nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359532(CHEMBL1927153)
Affinity DataKi:  112nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330738(2-(2-chloro-4-fluorophenyl)-5-(2-(pyridin-2-yl)eth...)
Affinity DataKi:  114nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330745(2-(2-chlorophenyl)-4-((4-fluorophenoxy)methyl)-5-m...)
Affinity DataKi:  114nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359533(CHEMBL1927154)
Affinity DataKi:  116nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330746(2-(2-chlorophenyl)-4-(2-fluorophenyl)-5-methyl-1H-...)
Affinity DataKi:  128nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359521(CHEMBL1927159)
Affinity DataKi:  131nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359526(CHEMBL1926690)
Affinity DataKi:  142nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359527(CHEMBL1927148)
Affinity DataKi:  144nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330739(2-(2-chlorophenyl)-4-((methyl(phenyl)amino)methyl)...)
Affinity DataKi:  151nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330737(4-((4-fluorophenoxy)methyl)-5-(2-methoxyethyl)-2-(...)
Affinity DataKi:  153nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359522(CHEMBL1927160)
Affinity DataKi:  156nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330718(2-(2-chlorophenyl)-4-methyl-5-(3-phenylprop-2-ynyl...)
Affinity DataKi:  158nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)
Affinity DataKi:  165nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330736(4-((benzyl(methyl)amino)methyl)-2-(2-chloro-4-fluo...)
Affinity DataKi:  165nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330741(2-(2-chlorophenyl)-4-((methyl(phenyl)amino)methyl)...)
Affinity DataKi:  172nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330734(4-Methyl-2-(2-methylphenyl)-5-(pyridine-2-ylmethyl...)
Affinity DataKi:  173nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330709(2-(2-chloro-4-fluorophenyl)-4,5-dimethyl-1H-pyrazo...)
Affinity DataKi:  213nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330704(2-(2-chlorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)
Affinity DataKi:  215nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330719(CHEMBL1276857 | N-(2-(2-chlorophenyl)-4-methyl-3,6...)
Affinity DataKi:  218nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330729(2-(2,5-dichlorobenzyl)-4-methyl-5-(pyridin-2-ylmet...)
Affinity DataKi:  218nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330733(2-(2-chloro-4-fluorophenyl)-4-methyl-5-(pyridin-2-...)
Affinity DataKi:  235nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330716(2-(2-chlorophenyl)-5-(2-(dimethylamino)ethyl)-4-me...)
Affinity DataKi:  235nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330723(2-(2-chlorophenyl)-4-methyl-5-((6-morpholinopyridi...)
Affinity DataKi:  236nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330703(1-acetyl-2-(2-chlorophenyl)-4-methyl-5-(pyridin-3-...)
Affinity DataKi:  240nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330721(4-((2-(2-chlorophenyl)-4-methyl-3,6-dioxo-2,3-dihy...)
Affinity DataKi:  259nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330732(2-(4-chlorobenzyl)-4-methyl-5-(pyridin-2-ylmethyl)...)
Affinity DataKi:  259nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330701(1-(2-(3-methoxyphenyl)acetyl)-4-methyl-2-phenyl-5-...)
Affinity DataKi:  285nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330711(3-(4,5-dimethyl-3,6-dioxo-5,6-dihydro-1H-pyrazolo[...)
Affinity DataKi:  293nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330705(2-(2-fluorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)
Affinity DataKi:  308nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330725(2-(2-methoxyethyl)-4-methyl-5-(pyridin-2-ylmethyl)...)
Affinity DataKi:  313nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330728(2-(2-(4-chlorophenoxy)ethyl)-4-methyl-5-(pyridin-2...)
Affinity DataKi:  326nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330713(CHEMBL1275631 | N-(3-(4,5-dimethyl-3,6-dioxo-5,6-d...)
Affinity DataKi:  328nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330727(4-methyl-2-phenethyl-5-(pyridin-2-ylmethyl)-1H-pyr...)
Affinity DataKi:  334nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330712(2-(3-chlorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)
Affinity DataKi:  340nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330731(2-(2-chloro-4-fluorobenzyl)-4-methyl-5-(pyridin-2-...)
Affinity DataKi:  342nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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