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Found 19 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-2'
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.726nMAssay Description:Inhibition of human p70S6Kb using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human p70S6Kb using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168247(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline-7-carboxy...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168248(CHEMBL192909 | {5-[3-(4-Carboxymethyl-thiophen-2-y...)
Affinity DataIC50:  640nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168244(4-(5-{3-[5-(3-Carboxy-propyl)-thiophen-2-yl]-benzo...)
Affinity DataIC50:  820nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168242(3-(5-{3-[5-(2-Carboxy-ethyl)-thiophen-2-yl]-benzo[...)
Affinity DataIC50:  870nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168241(6,7-Di-thiophen-2-yl-2,3-dihydro-1,4-dioxa-5,8-dia...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168239(7,8-Dimethoxy-2,3-di-thiophen-2-yl-pyrazino[2,3-b]...)
Affinity DataIC50:  1.14E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168236(CHEMBL193162 | {5-[3-(5-Carboxymethyl-thiophen-2-y...)
Affinity DataIC50:  1.28E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168235(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline | CHEMBL3...)
Affinity DataIC50:  1.36E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50583520(CHEMBL5094006)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human recombinant P70S6Kbeta expressed in Sf9 insect cells using [KKRNRTLTK] as substrate in presence of [33P]-ATP by radiometric hotsp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168243(3-(5-{3-[5-(2-Methoxycarbonyl-ethyl)-thiophen-2-yl...)
Affinity DataIC50:  6.13E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168246(2,3-Di-thiophen-2-yl-quinoxaline-6,7-diol | CHEMBL...)
Affinity DataIC50:  9.61E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168249(5-[3-(5-carboxythien-2-yl)benzo[g]quinoxalin-2-yl]...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human RPS6KB2 using [KKRNRTLTK] as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168250(CHEMBL192974 | {5-[3-(4-Methoxycarbonylmethyl-thio...)
Affinity DataIC50:  1.18E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168238(6,7-Dimethoxy-2,3-di-thiophen-2-yl-quinoxaline | C...)
Affinity DataIC50:  1.63E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168237(6,7-Di-thiophen-2-yl-2,3-dihydro-1,4-dioxa-5,8-dia...)
Affinity DataIC50:  2.34E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168240(6,7-Di-thiophen-2-yl-[1,3]dioxolo[4,5-g]quinoxalin...)
Affinity DataIC50:  2.85E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed