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Found 13 Enz. Inhib. hit(s) with Target = 'Tryptase gamma'
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM23891(3-amidinophenylalanine deriv., 35 | CHEMBL107955 |...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was tested for inhibition of tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50302107(CHEMBL567893 | Grassystatin A)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human lung tryptase gamma1 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067529(2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067528(3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067522(2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067524(3-(3-Carbamimidoyl-phenyl)-2-[2-(4-cyano-benzenesu...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067526(2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067523(2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067527(3-(4-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50067530(3-(4-Carbamimidoyl-phenyl)-2-[2-(4-cyano-benzenesu...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration of the compound against Tryptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50093153(CHEMBL306620 | Derivative of APC-2059)
Affinity DataKd:  0.100nMAssay Description:Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50093142(1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl...)
Affinity DataKd:  0.0700nMAssay Description:Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase gamma(Homo sapiens (Human))
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50093142(1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl...)
Affinity DataKd:  0.0700nMAssay Description:Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed