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Found 112 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 6'
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243934(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304425(2-(4-morpholinophenylamino)-4-(2,3,6-trifluorobenz...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244291(4-[(2-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243884(4-[(2,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244292(4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243933(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,5-triflu...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304429(2-[4-(4-{[7-(3,5-Difluorobenzyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243882(4-[(2,3-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243885(4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304433(7-(3,5-Difluorobenzyl)-N-[4-(4-methylpiperazin-1-y...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304428(2-[4-(4-{[7-(3,5-Difluorobenzyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243932(4-[(3,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304432(2-[4-(4-{[7-(3,5-Difluorobenzyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244256(4-Benzylamino-2-{[4-(4-methylpiperazin-1-yl)phenyl...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244258(4-(benzylamino)-2-(4-morpholinophenylamino)pyrimid...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244258(4-(benzylamino)-2-(4-morpholinophenylamino)pyrimid...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244257(4-Benzylamino-2-[(4-piperazin-1-ylphenyl)amino]-py...)
Affinity DataIC50:  7nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244331(4-[(2-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244329(4-[(2-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244294(4-[(2-Methylbenzyl)amino]-2-[(4-morpholin-4-ylphen...)
Affinity DataIC50:  11nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304434(7-(3,5-Difluorobenzyl)-N-(4-piperazin-1-ylphenyl)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244223(4-Benzylamino-2-{[4-(4-hydroxypiperidin-1-yl)pheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244259(4-Benzylamino-2-{[4-(1-methylpiperidin-4-yl)phenyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243794(4-[(3-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)
Affinity DataIC50:  19nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197554(2-(3-chloro-4-hydroxyphenethylamino)-4-(benzylamin...)
Affinity DataIC50:  21nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197554(2-(3-chloro-4-hydroxyphenethylamino)-4-(benzylamin...)
Affinity DataIC50:  21nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244330(4-[(2-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)
Affinity DataIC50:  22nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244369(4-{[2-(Methylsulfanyl)benzyl]amino}-2-[(4-morpholi...)
Affinity DataIC50:  23nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243725(4-[(3-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244332(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-trifluorom...)
Affinity DataIC50:  25nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304430(CHEMBL595488 | [4-(4-{[7-(3,5-Difluorobenzyl)-7H-p...)
Affinity DataIC50:  26nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50499614(CHEMBL3741938)
Affinity DataIC50:  28nMAssay Description:Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50370949(CHEMBL226930)
Affinity DataIC50:  30nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304431(CHEMBL594821 | N-{4-[4-(2-Aminoethyl)piperazin-1-y...)
Affinity DataIC50:  34nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243723(4-[(3-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)
Affinity DataIC50:  36nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50304435(7-(3-Fluorobenzyl)-N-(4-morpholin-4-ylphenyl)-7Hpy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244366(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-nitrobenzy...)
Affinity DataIC50:  38nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50499605(CHEMBL3741162)
Affinity DataIC50:  44nMAssay Description:Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50370952(CHEMBL228018)
Affinity DataIC50:  45nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244189(4-(Benzylamino)-2-{[2-(3,5-dichloro-4-hydroxypheny...)
Affinity DataIC50:  61nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50370950(CHEMBL387668)
Affinity DataIC50:  64nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244191(4-Benzylamino-2-{[4-(3-hydroxypropyl)phenyl]amino}...)
Affinity DataIC50:  81nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50370956(CHEMBL389647)
Affinity DataIC50:  83nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197567(2-(4-hydroxyphenethylamino)-4-(benzylamino)pyrimid...)
Affinity DataIC50:  88nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243934(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)
Affinity DataIC50:  88nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197567(2-(4-hydroxyphenethylamino)-4-(benzylamino)pyrimid...)
Affinity DataIC50:  88nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50499625(CHEMBL3741886)
Affinity DataIC50:  89nMAssay Description:Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence pol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244190(4-Benzylamino-2-{[4-(2-hydroxyethyl)phenyl]amino}p...)
Affinity DataIC50:  95nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244222(4-(Benzylamino)-2-{[4-(3-hydroxypyrrolidine-1-yl)p...)
Affinity DataIC50:  98nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50370951(CHEMBL427436)
Affinity DataIC50:  100nMAssay Description:Inhibition of STAT6 in human IL4-stimulated FW4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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