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Found 7 Enz. Inhib. hit(s) with Target = 'Trypanothione synthetase'
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50152094(CHEMBL3780789)
Affinity DataIC50:  93nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 50 uM p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM92592(DDD85811)
Affinity DataIC50:  95nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM92593(DDD86243)
Affinity DataIC50:  140nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM92590(DDD60632)
Affinity DataIC50:  273nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM92591(DDD73385)
Affinity DataIC50:  317nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50152094(CHEMBL3780789)
Affinity DataIC50:  620nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 0.5 mM ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50152095(CHEMBL3779908)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi strain CL Brener N-terminal poly-His tagged spermidine synthase expressed in Escherichia coli BL21(DE3) using 50 uM p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed