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Found 4 Enz. Inhib. hit(s) with Target = 'UDP-glucuronosyltransferase 1A8'
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  3.64E+3nMAssay Description:Substrate inhibition of human UGT1A8-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50088502(CHEBI:5970 | CHEMBL3527329)
Affinity DataKi:  2.26E+4nMAssay Description:Substrate inhibition of human recombinant UGT1A8 assessed as IRI-O-5-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50088502(CHEBI:5970 | CHEMBL3527329)
Affinity DataKi:  2.34E+4nMAssay Description:Substrate inhibition of human recombinant UGT1A8 assessed as IRI-O-4'-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  3.54E+5nMAssay Description:Inhibition of human recombinant UGT1A8 after 10 mins in presence of UDPGAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed