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Found 8 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor/Metabotropic glutamate receptor 5'
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463984(CHEMBL4241844)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463980(CHEMBL4246881)
Affinity DataIC50:  1.80E+3nMAssay Description:Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463985(CHEMBL4244406)
Affinity DataIC50:  4.50E+3nMAssay Description:Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463982(CHEMBL4239987)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463981(CHEMBL4242192)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463986(CHEMBL4246185)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50018958(CHEBI:75401 | QUINPIROLE)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463984(CHEMBL4241844)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed