Affinity DataKi: 0.700nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Inhibition of human PARP2 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP2 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP2 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:In order to test the selectivity of substituents on piperazinotriazole ring within the PARP family, the selectivity of compound S3 and positive compo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:In order to test the selectivity of substituents on piperazinotriazole ring within the PARP family, the selectivity of compound S3 and positive compo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair