Found 63 Enz. Inhib. hit(s) with Target = 'Protein-arginine deiminase type-2' TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataKi: 8.08E+3nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
Affinity DataKi: 1.97E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 2.13E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.76E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 1.79E+5nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
Affinity DataKi: 2.82E+5nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 2.82E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 2.86E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 5.54E+5nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 5.54E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 6.62E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 7.14E+5nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
Affinity DataKi: 7.39E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+6nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 1.39E+6nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 1.43E+6nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 1.79E+6nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: 1.84E+6nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 4.62E+6nMAssay Description:Inhibition of full length recombinant mouse N-terminal GST-tagged PAD2 expressed in baculovirus infected Sf9 cells using benzoyl arginine ethyl ester...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+6nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Irreversible inhibition of PAD2 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Irreversible inhibition of PAD2 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Irreversible inhibition of PAD2 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluoromet...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of PAD2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: <7.94E+4nMAssay Description:Inhibition of N-terminal 6His/FLAG-tagged recombinant human PAD2 (1 to 665 residues) expressed in baculovirus infected sf9 cells using N-a-benzoyl-L-...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: <7.94E+4nMAssay Description:Inhibition of N-terminal 6His/FLAG-tagged recombinant human PAD2 (1 to 665 residues) expressed in baculovirus infected sf9 cells using N-a-benzoyl-L-...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: <7.94E+4nMAssay Description:Inhibition of N-terminal 6His/FLAG-tagged recombinant human PAD2 (1 to 665 residues) expressed in baculovirus infected sf9 cells using N-a-benzoyl-L-...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: <7.94E+4nMAssay Description:Inhibition of N-terminal 6His/FLAG-tagged recombinant human PAD2 (1 to 665 residues) expressed in baculovirus infected sf9 cells using N-a-benzoyl-L-...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
TargetProtein-arginine deiminase type-2(Homo sapiens (Human))
The Scripps Research Institute-Florida
Curated by ChEMBL
The Scripps Research Institute-Florida
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of recombinant human 6His-tagged PAD2 assessed as reduction in residual activity preincubated for 15 mins followed by addition of N-benzoy...More data for this Ligand-Target Pair
