Affinity DataKi: 0.100nMAssay Description:Binding affinity towards human Retinoic acid receptor alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha [200-419]/gamma [183-417](Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Affinity DataKi: 1nM ΔG°: -47.8kJ/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha [200-419]/gamma [183-417](Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Affinity DataKi: 1nM ΔG°: -47.8kJ/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha [200-419](Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Affinity DataKi: 2nM ΔG°: -46.2kJ/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha [200-419](Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Affinity DataKi: 2.5nM ΔG°: -45.6kJ/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity towards human Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity against RAR alpha receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Selective activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: 306nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 487nMAssay Description:Binding affinity towards Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Binding affinity towards Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 695nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 764nMAssay Description:Binding affinity towards Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 821nMAssay Description:Binding affinity towards Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 834nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Synergistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 944nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Synergistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair