Found 43 Enz. Inhib. hit(s) with Target = 'Lymphocyte antigen 96' 
Affinity DataIC50: 200nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
TargetLymphocyte antigen 96/Toll-like receptor 4(Mus musculus)
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 4.22E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 6.83E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 9.08E+3nMAssay Description:Displacement of bis-ANS to recombinant human MD2 after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataKon: 0.703M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.85E+5nMAssay Description:Binding affinity to recombinant human 10His-tagged MD2 (Glu17 to Asn160 residues) expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding affinity to recombinant human MD2 assessed as dissociation constant up to 200 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.90nMAssay Description:Binding affinity to recombinant human MD2 assessed as dissociation constant up to 200 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.94E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.70E+6nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.20E+3nMAssay Description:Binding affinity to MD2 (unknown origin) assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.89E+5nMAssay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.695M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 1.10M-1s-1Assay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.40E+4nMAssay Description:Binding affinity to MD2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.25E+5nMAssay Description:In vitro inhibition against TXA2/PGH2 receptor using [3H]-SQ 29,548 as radioligand in human platelet membrane preparationMore data for this Ligand-Target Pair
Affinity DataKd: 7.11E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.95E+4nMAssay Description:Binding affinity to recombinant human MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.20E+4nMAssay Description:Binding affinity to human recombinant MD2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 650nMAssay Description:Binding affinity to human MD-2 (17 to 160 residues) assessed as reduction in MD-2 binding to human HMGB1 after 7 mins by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.70E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.00E+3nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.60E+5nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.79E+5nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.60E+3nMAssay Description:Binding affinity to MD2 (unknown origin) assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.40E+4nMAssay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKon: 1.22M-1s-1Assay Description:Binding affinity to recombinant human MD2 (17 to 160 residues) expressed in Escherichia coli BL21(DE3) cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
