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Found 112 Enz. Inhib. hit(s) with Target = 'Target of rapamycin complex 2 subunit MAPKAP1'
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50503131(CHEMBL4563142)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606735(CHEMBL5219718 | US11731973, Example 3)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606737(CHEMBL5218727 | US11731973, Example 5)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606736(CHEMBL5218916 | US11731973, Example 10)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606741(CHEMBL5219710 | US11731973, Example 1)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606733(CHEMBL5218988)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606739(CHEMBL5220152 | US11731973, Example 7)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606740(CHEMBL5220536 | US11731973, Example 30)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50348452(AZD-8055 | CHEMBL1801204 | US9102670, 1a)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606742(CHEMBL5220948 | US11731973, Example 9)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50:  5nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529393(CHEMBL4564479 | US11731973, Example 24)
Affinity DataIC50:  5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataIC50:  5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606738(CHEMBL5218590 | US11731973, Example 6)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM582479(5-(2-aminobenzoxazol-5-yl)-7-methyl-7-methylsulfan...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: <10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM582478(5-(2-aminobenzoxazol-5-yl)-7-isobutyl-6, 7-dihydro...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529395(CHEMBL4529672 | US11731973, Example 21)
Affinity DataIC50:  11nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50535043(CHEMBL4577549)
Affinity DataIC50:  15nMAssay Description:Inhibition of mTORC2 in HEK293T/17 cells assessed as reduction in Akt phosphorylation at Ser-473 residue after 2 hrs by sandwich immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606734(CHEMBL5221072)
Affinity DataIC50:  16nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546183(CHEMBL4744705)
Affinity DataIC50:  17nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529407(CHEMBL4572049)
Affinity DataIC50:  20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529398(CHEMBL4549761 | US11731973, Example 31)
Affinity DataIC50:  20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606762(CHEMBL5218550)
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606764(CHEMBL5220568)
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606763(CHEMBL5219551)
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606761(CHEMBL5220263)
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606765(CHEMBL5219300)
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546183(CHEMBL4744705)
Affinity DataIC50:  34nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50515198(CHEMBL4445573)
Affinity DataIC50:  35nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50431522(CHEMBL2348865)
Affinity DataIC50:  40nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50431521(CHEMBL2348864)
Affinity DataIC50:  46nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606704(CHEMBL5218488)
Affinity DataIC50:  54nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529405(CHEMBL4588610)
Affinity DataIC50:  60nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546184(CHEMBL4758284)
Affinity DataIC50:  64nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546185(CHEMBL4749136)
Affinity DataIC50:  73nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50515201(CHEMBL4453693)
Affinity DataIC50:  74nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50505407(CHEMBL4436124)
Affinity DataIC50:  77nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529399(CHEMBL4538004)
Affinity DataIC50:  80nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50503139(CHEMBL1242115)
Affinity DataIC50:  80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataIC50:  80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  83nMAssay Description:Inhibition of recombinant mTORC2 (unknown origin) expressed in Escherichia coli after 15 mins in presence of gamma-[32]P-ATP by high-throughput scree...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546186(CHEMBL4754767)
Affinity DataIC50:  84nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529402(CHEMBL4517253)
Affinity DataIC50:  90nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529396(CHEMBL4538629)
Affinity DataIC50:  90nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50505410(CHEMBL4551080)
Affinity DataIC50:  94nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606705(CHEMBL5218661)
Affinity DataIC50:  106nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50505419(CHEMBL4474564)
Affinity DataIC50:  116nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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