Compile Data Set for Download or QSAR
maximum 50k data
Found 37 of ic50 for UniProtKB: O60894
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541411(CHEMBL4643006)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human CLR/RAMP1 by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541409(CHEMBL4647045)
Affinity DataIC50:  0.0450nMAssay Description:Inhibition of human CLR/RAMP1 by cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541412(CHEMBL4644508)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541404(CHEMBL4639133)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50047356(CHEMBL3334624)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217493(CHEMBL235237 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541403(CHEMBL4641806)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217485(CHEMBL394229 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217495(CHEMBL429262 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  36nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184071((R)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(2-...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184072((R)-4-(2-oxo-1,2,4,5-tetrahydrobenzo[d][1,3]diazep...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50047357(CHEMBL3334623)
Affinity DataIC50:  44nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217488(CHEMBL392132 | N-((3R,6S)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217486((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217486((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217498((R,Z)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184074((R)-N-(3-(3,5-dibromo-4-hydroxyphenyl)-1-oxo-1-(4-...)
Affinity DataIC50:  75nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217483((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-5-phe...)
Affinity DataIC50:  133nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217483((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-5-phe...)
Affinity DataIC50:  141nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541402(CHEMBL4645875)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217490(CHEMBL428547 | N-((3R,7R)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  408nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217482(CHEMBL236516 | tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2...)
Affinity DataIC50:  471nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217491((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...)
Affinity DataIC50:  488nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217491((cis racemic)-N-((3R)-1-(cyclopropylmethyl)-2-oxo-...)
Affinity DataIC50:  488nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184068((R)-N-(1-ethyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  990nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50541401(CHEMBL4634626)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184075((R)-4-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)-N-(...)
Affinity DataIC50:  1.58E+3nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184076((R,S)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)
Affinity DataIC50:  1.81E+3nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217482(CHEMBL236516 | tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2...)
Affinity DataIC50:  2.12E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217489((R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(...)
Affinity DataIC50:  2.40E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217492(CHEMBL238203 | N-(1-isopropyl-2-oxo-2,3,4,5-tetrah...)
Affinity DataIC50:  3.10E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184070((R)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataIC50:  3.64E+3nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50184067((S)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataIC50:  4.45E+3nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50217496(CHEMBL235015 | N-((3S,6R)-1-(cyclopropylmethyl)-2-...)
Affinity DataIC50:  6.63E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50173483((S)-6-Amino-2-[(R)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed