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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 459193   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM459193
PNG
(US10759799, Compound 45)
Show SMILES CN1CCCn2cc(nn2)-c2cncc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(C1)c2
Show InChI InChI=1S/C25H20N10/c1-34-5-2-6-35-14-22(31-33-35)19-11-27-12-21-23(19)29-25(28-21)24-18-8-16(3-4-20(18)30-32-24)17-7-15(13-34)9-26-10-17/h3-4,7-12,14H,2,5-6,13H2,1H3/b25-24+
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...


US Patent US10759799 (2020)

More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM459193
PNG
(US10759799, Compound 45)
Show SMILES CN1CCCn2cc(nn2)-c2cncc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(C1)c2
Show InChI InChI=1S/C25H20N10/c1-34-5-2-6-35-14-22(31-33-35)19-11-27-12-21-23(19)29-25(28-21)24-18-8-16(3-4-20(18)30-32-24)17-7-15(13-34)9-26-10-17/h3-4,7-12,14H,2,5-6,13H2,1H3/b25-24+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...


US Patent US10759799 (2020)

More data for this
Ligand-Target Pair