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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50354013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50354013
PNG
(CHEMBL1828898)
Show SMILES CCCN(CCC)c1cc(nc2ccnn12)N(CCC)c1ccc(OC)cc1Cl
Show InChI InChI=1S/C22H30ClN5O/c1-5-12-26(13-6-2)22-16-21(25-20-10-11-24-28(20)22)27(14-7-3)19-9-8-17(29-4)15-18(19)23/h8-11,15-16H,5-7,12-14H2,1-4H3
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MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 75.7n/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...


Bioorg Med Chem 19: 5955-66 (2011)


Article DOI: 10.1016/j.bmc.2011.08.055
BindingDB Entry DOI: 10.7270/Q24X5862
More data for this
Ligand-Target Pair