Found 7 of ic50 for monomerid = 1 TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibitory activity (50 uM) against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with BVAraUMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory activity (50 uM) against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with gancicclovirMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
3D Structure (crystal)TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against HSV-1 TK (WT) catalyzed [3H]-GCV phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylationMore data for this Ligand-Target Pair
Affinity DataKi: 1.54E+4nM IC50: 2.10E+4nMAssay Description:Ketotifen, dacarbazine, thiocolchicoside, meloxicam, methotrexate, furosemide, olanzapine, methylprednizolone acetate, paricalcitol, ritodrine hydroc...More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against HSV-1 TK (A167Y) catalyzed [3H]-GCV phosphorylationMore data for this Ligand-Target Pair
