Compile Data Set for Download or QSAR
maximum 50k data
Found 2 of ic50 for monomerid = 113238
TargetBeta-secretase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113238(US10336717, Compound 16 | US8633212, 16)
Affinity DataIC50:  11.5nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113238(US10336717, Compound 16 | US8633212, 16)
Affinity DataIC50:  11.5nMpH: 4.5 T: 2°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity. The assay was performed at room temperature in 96-well...More data for this Ligand-Target Pair
In DepthDetails US Patent