Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for monomerid = 119292
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  2nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  2nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  7nMAssay Description:Inhibition of PI3Kbeta in PTEN-null human MDA-MB-468 cells assessed as inhibition of Akt phosphorylation after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant PI3Kbeta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  59nMAssay Description:Inhibition of human recombinant PI3Kdelta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant PI3Kalpha using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM119292(US8673906, 4.11 | US9718800, 4.11)
Affinity DataIC50:  930nMAssay Description:Inhibition of human recombinant PI3Kgamma using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed