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Found 4 of ic50 for monomerid = 15374
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM15374(9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM15374(9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Her2 in human MCF7 cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Ribotargets

Curated by ChEMBL
LigandPNGBDBM15374(9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ATP-ase activity in human colon tumour cell line (HCT116)More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
Vernalis (R&D)

LigandPNGBDBM15374(9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...)
Affinity DataIC50: >2.00E+5nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed