BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 180921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinamide phosphoribosyltransferase (NAMPT)


(Homo sapiens (Human))
BDBM180921
PNG
(US9676721, 79 2-cyano-1-{[4-(1-methyl-1H-indazole-...)
Show SMILES Cn1ncc2ccc(cc12)S(=O)(=O)c1ccc(CN\C(Nc2ccncc2)=N/C#N)cc1
Show InChI InChI=1S/C22H19N7O2S/c1-29-21-12-20(7-4-17(21)14-27-29)32(30,31)19-5-2-16(3-6-19)13-25-22(26-15-23)28-18-8-10-24-11-9-18/h2-12,14H,13H2,1H3,(H2,24,25,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a7.525



FORMA TM, LLC

US Patent


Assay Description
The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...


US Patent US9676721 (2017)


BindingDB Entry DOI: 10.7270/Q2VD6WMM
More data for this
Ligand-Target Pair