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Found 5 of ic50 for monomerid = 18240
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  12nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  13nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  21nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  35nMpH: 7.4 T: 2°CAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus cereus (ATCC 14579))
University Of Connecticut At Storrs

LigandPNGBDBM18240(2,4-diamino-5-deazapteridine, 9 | Piritrexim analo...)
Affinity DataIC50:  1.85E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed