Affinity DataIC50: 10nMAssay Description:Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet-type 12-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of His-tagged human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187-stimulated LTB4 production prei...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of RBL-1 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against soybean 1-lipoxygenase (SLO)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of His-tagged human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibitory activity of the compound against rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against RBL-1 5-LOMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
San Francisco State University
Curated by ChEMBL
San Francisco State University
Curated by ChEMBL
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of 15 LOXMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against human platelet 12-lipoxygenase (12-HLO)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human 15-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DHT from human androgen receptor expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...More data for this Ligand-Target Pair
Affinity DataIC50: 3.88E+4nMAssay Description:Transcriptional activity at human androgen receptor BF3 site stably transfected in eGFP-expressing human LNCAP cells after 5 days by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of 5-iodoacetamidofluorescein labeled SRC23 peptide CKENALLRYLLDKDD human androgen receptor AF2 site expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair