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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 274779   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I delta/epsilon


(Homo sapiens (Human))
BDBM274779
PNG
(N-(6-(4-(4-fluorophenyl)-1,2- dimethyl-1H-imidazol...)
Show SMILES Cc1nc(c(-c2ccc3nc(NC(=O)c4cocn4)cn3n2)n1C)-c1ccc(F)cc1
Show InChI InChI=1S/C21H16FN7O2/c1-12-24-19(13-3-5-14(22)6-4-13)20(28(12)2)15-7-8-18-25-17(9-29(18)27-15)26-21(30)16-10-31-11-23-16/h3-11H,1-2H3,(H,26,30)
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.80n/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...


US Patent US9556179 (2017)

More data for this
Ligand-Target Pair
Casein kinase I Epsilon


(Homo sapiens (Human))
BDBM274779
PNG
(N-(6-(4-(4-fluorophenyl)-1,2- dimethyl-1H-imidazol...)
Show SMILES Cc1nc(c(-c2ccc3nc(NC(=O)c4cocn4)cn3n2)n1C)-c1ccc(F)cc1
Show InChI InChI=1S/C21H16FN7O2/c1-12-24-19(13-3-5-14(22)6-4-13)20(28(12)2)15-7-8-18-25-17(9-29(18)27-15)26-21(30)16-10-31-11-23-16/h3-11H,1-2H3,(H,26,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 38.7n/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...


US Patent US9556179 (2017)

More data for this
Ligand-Target Pair