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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 326284   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))
BDBM326284
PNG
(US9637488, 67)
Show SMILES Nc1ncnc(N2CCCC2c2cc3cccc(Cl)c3nc2-c2ccccc2)c1C#N
Show InChI InChI=1S/C24H19ClN6/c25-19-9-4-8-16-12-17(21(30-22(16)19)15-6-2-1-3-7-15)20-10-5-11-31(20)24-18(13-26)23(27)28-14-29-24/h1-4,6-9,12,14,20H,5,10-11H2,(H2,27,28,29)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<0.0500n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...


US Patent US9637488 (2017)

More data for this
Ligand-Target Pair