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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 337239   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)


(Homo sapiens (Human))
BDBM337239
PNG
(N-[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-...)
Show SMILES Fc1cccc(CC(=O)Nc2ccc3ncc(-c4cc5ccccc5o4)n3n2)c1
Show InChI InChI=1S/C22H15FN4O2/c23-16-6-3-4-14(10-16)11-22(28)25-20-8-9-21-24-13-17(27(21)26-20)19-12-15-5-1-2-7-18(15)29-19/h1-10,12-13H,11H2,(H,25,26,28)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...


US Patent US9745304 (2017)

More data for this
Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)


(Homo sapiens (Human))
BDBM337239
PNG
(N-[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-...)
Show SMILES Fc1cccc(CC(=O)Nc2ccc3ncc(-c4cc5ccccc5o4)n3n2)c1
Show InChI InChI=1S/C22H15FN4O2/c23-16-6-3-4-14(10-16)11-22(28)25-20-8-9-21-24-13-17(27(21)26-20)19-12-15-5-1-2-7-18(15)29-19/h1-10,12-13H,11H2,(H,25,26,28)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...


US Patent US9745304 (2017)

More data for this
Ligand-Target Pair