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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 339251   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM339251
PNG
(US10201546, Example 125c)
Show SMILES COc1nc2ccc(cc2c(Cl)c1CN1CCC(CC1)C(F)(F)F)[C@](O)(C1CN(C1)C(C)=O)c1ccnc(c1)C(F)(F)F
Show InChI InChI=1S/C29H29ClF6N4O3/c1-16(41)40-13-20(14-40)27(42,19-5-8-37-24(12-19)29(34,35)36)18-3-4-23-21(11-18)25(30)22(26(38-23)43-2)15-39-9-6-17(7-10-39)28(31,32)33/h3-5,8,11-12,17,20,42H,6-7,9-10,13-15H2,1-2H3/t27-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
A reporter assay was used to test functional activity of RORγt modulatory compounds on transcriptional activation driven by the RORγt LBD. ...


US Patent US10201546 (2019)

More data for this
Ligand-Target Pair