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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 352087   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM352087
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-{[6-(...)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cccc1F
Show InChI InChI=1/C23H24F3N5/c1-14-9-15(27)13-31(12-14)21-7-8-28-11-20(21)29-10-16-5-6-19(26)23(30-16)22-17(24)3-2-4-18(22)25/h2-8,11,14-15,29H,9-10,12-13,27H2,1H3/t14-,15+/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM352087
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-{[6-(...)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cccc1F
Show InChI InChI=1/C23H24F3N5/c1-14-9-15(27)13-31(12-14)21-7-8-28-11-20(21)29-10-16-5-6-19(26)23(30-16)22-17(24)3-2-4-18(22)25/h2-8,11,14-15,29H,9-10,12-13,27H2,1H3/t14-,15+/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM352087
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-{[6-(...)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cccc1F
Show InChI InChI=1/C23H24F3N5/c1-14-9-15(27)13-31(12-14)21-7-8-28-11-20(21)29-10-16-5-6-19(26)23(30-16)22-17(24)3-2-4-18(22)25/h2-8,11,14-15,29H,9-10,12-13,27H2,1H3/t14-,15+/s2
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair